MyBioSource.com's MBTPS2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence. The MBTPS2 Antibody was generated using MBTPS2 as the antigen and it reacts with Human.
Description
Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.Rawson R.B., Mol. Cell 1:47-57(1997).Ye J., Proc. Natl. Acad. Sci. U.S.A. 97:5123-5128(2000)